After 12 years’ development, CHInano has become China’s biggest and most influential nanotech industry exchange event and received broad recognition and participation from countries all over the world that take a strong lead in the nanotech industry. As the most important part of the event, the world’s top scientists and talents are attracted to deliver plenary speeches. In 2021, four distinguished guests have confirmed their participation: they are Mr. Konstantin Novoselov, 2010 Nobel Prize Laureate in Physics, Professor of University of Manchester;Mr.Sean Ding,Managing Partner and Chief Scientist of Vanke Service BG, Global Director of the MEMS & Sensors Industry Group (MSIG);Mr Niels Peter Thomas，President, Greater China Managing Director Books,Springer Nature；and Mr Tetsuro Homma,Representative Director, Member of the Board Executive Vice President Regional Head of China & Northeast Asia .These four guests shared with us the latest findings and trends in the research and development in nanotech development, nanoparticle manufacturing and nanotech innovation, etc.